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Our group research bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Handle.
Multicolor imaging in the bacterial nucleoid and cell division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins
Deposition and atomic pressure microscopy of specific phthalocyanine polymers amongst nanofabricated electrodes
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Our study ranges in the biophysics of DNA to synthetic cells and beyond. Please take a look down below within the spectrum of our present-day jobs.
Given that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from DNA supercoiling scientific tests of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Lately his research has centered on learning mobile division with micro organism on chip, even though his greatest desire is while in the path of knowing synthetic cells.
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‘Of course, I have an understanding of individuals have been amazed at some time. At the conclusion of the nineties, when I was in my forties, I was Professor of Molecular Electronics and I have to admit that it had become a bit bored, I didn’t study much any more. The field went much more into the appliance aspect, how you might combine nanotubes into Digital circuits.
Pretty great, but that wasn’t seriously where by my fascination lay. I needed to pioneer and I had the feeling that was no more probable, because the most attention-grabbing elementary insights experienced currently been uncovered. But my discipline experienced made numerous enjoyable new applications to measure personal molecules. I made a decision which i needed to apply this to biology, to look at it from a Bodily viewpoint.’
In 1993 he was appointed as Associate Professor at Delft College of Technologies. While in the mid-nineteen nineties Dekker and his team reached achievements with the discovery in the Digital Attributes of carbon nanotubes, the very first solitary-molecule transistor together with other ceesdekker nanoscience.
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Developments in nanotechnology while in the nineties manufactured making Digital products from solitary molecules a likelihood. Cees Dekker recounts how his crew designed a place-temperature transistor based upon one carbon nanotube.
Solid-state nanopores have verified for being a amazingly versatile probe for one-molecule Investigation of DNA. I will describe some of our the latest conclusions – exclusively DNA knots – along with our efforts to extend the abilities of sound-state nanopores even further, during the course of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.